Detalhe da pesquisa
1.
Andrographolide: A Diterpenoid from Cymbopogon schoenanthus Identified as a New Hit Compound against Trypanosoma cruzi Using Machine Learning and Experimental Approaches.
J Chem Inf Model
; 64(7): 2565-2576, 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148604
2.
Energy metabolism as a target for cyclobenzaprine: A drug candidate against Visceral Leishmaniasis.
Bioorg Chem
; 127: 106009, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35841672
3.
Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murine Leishmania (L.) amazonensis model.
Drug Dev Res
; 83(2): 285-295, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32767443
4.
Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface.
Bioorg Chem
; 84: 186-191, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30502630
5.
Nanoliposomal Buparvaquone Immunomodulates Leishmania infantum-Infected Macrophages and Is Highly Effective in a Murine Model.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28167544
6.
Activity of imidazole compounds on Leishmania (L.) infantum chagasi: reactive oxygen species induced by econazole.
Mol Cell Biochem
; 389(1-2): 293-300, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24374794
7.
Insulin-like growth factor-I induces arginase activity in Leishmania amazonensis amastigote-infected macrophages through a cytokine-independent mechanism.
Mediators Inflamm
; 2014: 475919, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25294956
8.
Saturated Iso-Type Fatty Acids from the Marine Bacterium Mesoflavibacter zeaxanthinifaciens with Anti-Trypanosomal Potential.
Pharmaceuticals (Basel)
; 17(4)2024 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675459
9.
Multitarget anti-parasitic activities of isoquinoline alkaloids isolated from Hippeastrum aulicum (Amaryllidaceae).
Phytomedicine
; 128: 155414, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503155
10.
Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi.
Exp Parasitol
; 135(4): 655-60, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24113627
11.
The Potential of Secondary Metabolites from Plants as Drugs or Leads against Trypanosoma cruzi-An Update from 2012 to 2021.
Curr Top Med Chem
; 23(3): 159-213, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36515019
12.
Identification of inhibitors as drug candidates against Chagas disease.
Eur J Med Chem
; 248: 115074, 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36623331
13.
Effect of partial O-methylation in dehydrodieugenol on its antitrypanosomal activity - correlation with the toxicity using cell membrane models.
Biophys Chem
; 296: 106975, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36842251
14.
Evaluation of antileishmanial potential of the antidepressant escitalopram in Leishmania infantum.
J Pharm Biomed Anal
; 209: 114469, 2022 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838348
15.
A new reduced chalcone-derivative affects the membrane permeability and electric potential of multidrug-resistant Enterococcusfaecalis.
Chem Biol Interact
; 365: 110086, 2022 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35940279
16.
Investigation into in vitro anti-leishmanial combinations of calcium channel blockers and current anti-leishmanial drugs.
Mem Inst Oswaldo Cruz
; 106(8): 1032-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22241129
17.
Bioenergetics impairment of Trypanosoma cruzi by the antihypertensive manidipine: A drug repurposing strategy.
Acta Trop
; 214: 105768, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33245907
18.
Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera.
Planta Med
; 76(13): 1454-6, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20301059
19.
Furazolidone is a selective in vitro candidate against Leishmania (L.) chagasi: an ultrastructural study.
Parasitol Res
; 106(6): 1465-9, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20352451
20.
Targeting intracellular Leishmania (L.) infantum with nitazoxanide entrapped into phosphatidylserine-nanoliposomes: An experimental study.
Chem Biol Interact
; 332: 109296, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33096056